Journal of Indian Academy of Oral Medicine and Radiology

RESEARCH AND EMERGING TRENDS
Year
: 2005  |  Volume : 17  |  Issue : 4  |  Page : 161--164

Immunological and Biochemical Markers in Oral Pre-cancer and Cancer : A Study


Sunali Khanna, Freny Karjodkar 
 Department of Oral Medicine & Radiology, Nair Hospital Dental College, Mumbai 400 008, India

Correspondence Address:
Sunali Khanna
Department of Oral Medicine & Radiology, Nair Hospital Dental College, Mumbai 400 008
India

Oral cancer, the sixth most common cancer worldwide remains, continues to be the most prevalent cancer related to the consumption of tobacco, alcohol and other carcinopenic products. Serum levels of circulating immune complexes, trace elements (copper, iron and selemium) were evaluated in 30 patients with OSMF (Oral submucous fibrosis)/leukoplakia, 30 patients with squrmous cell carcinoma and 30 normal subjects. There was a significant increase in the circulating immune complexes in the pre cancer and cancer patients. Serum copper levels showed gradual increase from pre cancer to cancer group. However, serum iron levels were decreaed significantly in the cancer group. Serum selenium levels were also decreased significantly in cancer group. Among, circulating immune complexes, serum copper, iron and selenium the best predictors for the occurrence of lesion were age, serum iron, circulating immune complexes and serum selenium in the decreasing order.


How to cite this article:
Khanna S, Karjodkar F. Immunological and Biochemical Markers in Oral Pre-cancer and Cancer : A Study.J Indian Acad Oral Med Radiol 2005;17:161-164


How to cite this URL:
Khanna S, Karjodkar F. Immunological and Biochemical Markers in Oral Pre-cancer and Cancer : A Study. J Indian Acad Oral Med Radiol [serial online] 2005 [cited 2023 Feb 4 ];17:161-164
Available from: http://www.jiaomr.in/article.asp?issn=0972-1363;year=2005;volume=17;issue=4;spage=161;epage=164;aulast=Khanna;type=0