| CASE REPORT |
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| Year : 2022 | Volume
: 34
| Issue : 4 | Page : 484-487 |
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“Fruit in a tooth” - A rare non - Syndromic anomaly - 2 rare case reports with a genetic analysis
Arul Jothi Murugan, G Anuradha, A Kannan, Krithika Chandrasekar Lakshmi
Department of Oral Medicine and Radiology, SRM Dental College, Ramapuram, Chennai, Tamil Nadu, India
Correspondence Address:
Arul Jothi Murugan
Department of Oral Medicine and Radiology, SRM Dental College, Ramapuram, Chennai, Tamil Nadu
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jiaomr.jiaomr_84_22
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Tooth agenesis is one of the most common developmental anomalies affecting function and aesthetics. Genetic mutations cause non-syndromic tooth agenesis and involve the interaction of genes of tooth epithelium and mesenchyme odontogenesis. This article is the first in the literature to present non-syndromic cases of two siblings reported with mulberry molars, morphological changes in teeth (hypodontia and microdontia), and a genetic study performed to substantiate the involvement of Paired box gene 9 in tooth agenesis and morphogenesis.
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