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Year : 2019  |  Volume : 31  |  Issue : 4  |  Page : 311-317

A Study to Evaluate the Efficacy of Platelet Rich Fibrin with Nanocrystalline Beta-Tricalcium Phosphate in the Treatment of Periodontal Intrabony Defects

1 Department of Dentistry, Oral Medicine and Radiology, IGIMS, Patna, Bihar, India
2 Department of Periodontics, Buddha Institute of Dental Sciences and Hospital, Patna, Bihar, India

Correspondence Address:
Dr. Sneha Mayuri
Department of Periodontics, Buddha Institute of Dental Sciences and Hospital, Patna, Bihar; C/O Dr. Naresh Prasad, Ayodhya Niwas, 85-A Block, Road No-2B, Rajendra Nagar, Patna - 800 016, Bihar
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jiaomr.jiaomr_202_19

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Background: Presently, there is no gold-standard regenerative material for the treatment of periodontal intrabony defects. The use of bone grafts in combination with guided tissue regeneration membrane is a predictable treatment option but is expensive. Platelet concentrates are increasingly being used due to their ease of use and cost-effectiveness. Aims: The objective of the present study is to compare clinically and also by Cone Beam Computed Tomography (CBCT), the effect of platelet-rich fibrin combined with synthetic beta-tricalcium phosphate to synthetic beta-tricalcium phosphate alone in the treatment of periodontal intrabony defects. Materials and Methods: 10 patients possessing 2 almost identical interproximal intrabony defects in either side of mandible were selected and the defects were further divided into 2 groups randomly: Control Group A (Beta-tricalcium phosphate placed) and Test Group B (Beta-tricalcium phosphate with platelet-rich fibrin placed). Regeneration of soft tissue and hard tissue (using CBCT) were evaluated after 6 months from baseline in both groups. Statistical Analysis Used: The intragroup and intergroup comparisons were done using Paired and student t-test. Results: Intragroup showed significant improvement in both soft tissue and hard tissue parameters. Mean of all parameters was better in the test group; however, the intergroup difference was not statistically significant. Conclusions: Within the limitations of the present study, the use of beta-tricalcium phosphate bone graft combined with platelet-rich fibrin and beta-tricalcium phosphate bone graft alone are both equally effective for the treatment of periodontal intrabony defects.

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