| ORIGINAL ARTICLE |
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| Year : 2019 | Volume
: 31
| Issue : 4 | Page : 286-292 |
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A novel mixture of curcumin paste and prednisolone for treating oral lichen planus: A case controlled comparative study
Shantala R Naik1, Prashant Gupta1, L Ashok2, Tanya Khaitan1, Anjani K Shukla1
1 Dental Institute, Rajendra Institute of Medical Sciences, Bariatu, Ranchi, Jharkhand, India
2 Bapuji Dental College and Hospital, MCC B Block, Davangere, Karnataka, India
Correspondence Address:
Dr. Prashant Gupta
Department of Oral Medicine and Radiology, Dental Institute, Rajendra Institute of Medical Sciences, Bariatu, Ranchi, Jharkhand
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jiaomr.jiaomr_171_19
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Background and Aims: This study was done to evaluate the clinical efficacy as a topical drug of a novel mixture of prednisolone and curcumin in oral lichen planus. Methods: Our study included 60 cases of symptomatic oral lichen planus. Patients were divided into two groups of 30 each. Group 1 received first mode of therapy of topical curenext gel. Group 2 received second mode of therapy of novel mixture of curenext gel and prednisolone. They were reviewed after 10 days and 20 days. Findings: Novel mixture effectively reduced the reticulation, erosion and pain and these differences were significant when compared with first mode of therapy. Conclusion: We would recommend the use of novel mixture for treatment of any case of symptomatic oral lichen planus than using curenext alone. Practical Implications: Topical curcumin alone is not effective against oral lichen planus. If this is mixed with a steroid, the mixture could give the benefits of steroid and curcumin together and hence appear to be more effective.
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