Home About us Editorial board Ahead of print Current issue Archives Submit article Instructions Subscribe Search Contacts Login 
  • Users Online: 984
  • Home
  • Print this page
  • Email this page
Year : 2019  |  Volume : 31  |  Issue : 2  |  Page : 128-133

Estimation of the level of salivary proinflammatory cytokine in oral lichen planus – A case–control study in cuddalore-based population

1 Department of Oral Medicine and Radiology, RVS Dental College and Hospital, Coimbatore, Tamil Nadu, India
2 Department of Oral Medicine and Radiology, Rajah Muthiah Dental College and Hospital, Annamalai University, Chidambaram, Tamil Nadu, India
3 Department of Oral and Maxillofacial Surgery, Sri Ramakrishna Dental College and Hospital, Coimbatore, Tamil Nadu, India

Correspondence Address:
Dr. J Nandhini
Department of Oral Medicine and Radiology, RVS Dental College and Hospital, Coimbatore - 641 402, Tamil Nadu
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jiaomr.jiaomr_43_19

Rights and Permissions

Aim: To estimate and compare the proinflammatory cytokine [tumor necrosis factor (TNF)-α] level in the saliva of oral lichen planus (OLP) and controls. Materials and Methods: A total of 22 OLP cases who were clinically and histopathologically proven (12 male and 10 female patients, with a mean age of 42 years) and 22 controls matched for age, sex, and socioeconomic status were enrolled in the study. Salivary TNF-α level was analyzed by immunoassay kits. Statistical Package for Social Science version 21.0 software was used for data analysis. Results: The salivary TNF-α level was significantly higher (P < 0.001) in patients than in controls. Conclusion: The results suggest that TNF-α may be a good diagnostic biomarker for this potentially malignant disorder.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded268    
    Comments [Add]    

Recommend this journal