Marfan Syndrome: A Report of Two Cases and Review

K Vinay Kumar Reddy; T Venkata Satya Ramesh; D Koteeswaran; M Jayakiran; Y Sivaranjani

doi:10.5005/jp-journals-10011-1139

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CASE REPORT

Year : 2011 | Volume : 23 | Issue : 3 | Page : 248-251

Marfan Syndrome: A Report of Two Cases and Review

K Vinay Kumar Reddy¹, T Venkata Satya Ramesh², D Koteeswaran³, M Jayakiran⁴, Y Sivaranjani⁴
¹ Department of Oral Medicine and Radiology, Mamata Dental College and Hospital Khammam, Andhra Pradesh, India
² Department of Oral Medicine and Radiology, Mamata Dental College and Hospital, Khammam, Andhra Pradesh, India
³ Department of Oral Medicine and Radiology, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu, India
⁴ Department of Oral and Maxillofacial Pathology, Mamata Dental College and Hospital, Khammam, Andhra Pradesh, India

Correspondence Address:
K Vinay Kumar Reddy
Department of Oral Medicine and Radiology, Mamata Dental College and Hospital, Staff Quarters, Penna G-4 Marnata Hospital Campus, Ginprasad Nagar, Khammam, Andhra Pradesh
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.5005/jp-journals-10011-1139

Marfan syndrome is an autosomal dominant disorder of the connective tissues, resulting in abnormalities of the musculoskeletal system, cardiovascular system and eyes. It has a prevalence of 1 in 100,000 population and occurs in all ethnic groups. It may be familial or due to new mutation (30%), in the fibrillin gene on arm of chromosome 15. It is estimated that one person in every 3000 to 5000 has Marfan's syndrome may have cardiovascular abnormalities and may be complicated by infective endocarditis. About 90% of Marfan patients will develop cardiac complications.

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