| EMERGING TRENDS |
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| Year : 2007 | Volume
: 19
| Issue : 4 | Page : 503-511 |
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Current Pathophysiological Aspects and Therapeutic Modalities for Pemphigus Vulgaris : A Review
J Raviraj1, Ajay G Nayak2
1 Department of Oral Medicine & Radiology, Rama Dental College Hospital and Research Centre, Kanpur, Uttar Pradesh - 208024, India
2 Department of Oral Medicine & Radiology, Yenepoya Dental College & Hospital, Nithyanand Nagar Post, Deralakatte, Mangalore - 18, India
Correspondence Address:
J Raviraj
Department of Oral Medicine & Radiology, Rama Dental College Hospital and Research Centre, Kanpur, Uttar Pradesh - 208024
India
 Source of Support: None, Conflict of Interest: None  | Check |
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Pemphigus vulgaris (PV) is an autoimmune disorder manifesting primarily as blisters involving the mucocutaneous systems. The current medical literature indicates many breakthroughs in the research of pathophysiology and treatment aspects of PV. This article tries to describe some of the novel aspects briefing the role of nondesmoglein antibodies and the role of TNF-alpha in the etiopathogenesis of pemphigus vulgaris and the role of newer therapeutic modalities like Rituximab, Etanercept, intravenous Immunoglobulins, cholinergic drugs, arid the like in the treatment of PV.
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